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The Wood–Ljungdahl pathway is a set of biochemical reactions used by some bacteria and archaea. It is also known as the reductive acetyl-coenzyme A (Acetyl-CoA) pathway.〔 This pathway enables certain organisms to use hydrogen as an electron donor and carbon dioxide as an electron acceptor as well as a building block for biosynthesis. In this pathway carbon dioxide is reduced to carbon monoxide and formic acid or directly into a formyl group, the formyl group is reduced to a methyl group and then combined with the carbon monoxide and Coenzyme A to produce acetyl-CoA. Two specific enzymes participate on the carbon monoxide side of the pathway: CO Dehydrogenase and acetyl-CoA synthase. The former catalyzes the reduction of the CO2 and the latter combines the resulting CO with a methyl group to give acetyl-CoA.〔Stephen W. Ragsdale "Metals and Their Scaffolds To Promote Difficult Enzymatic Reactions" Chem. Rev. 2006, 106, 3317–3337. 〕〔Paul A. Lindahl "Nickel-Carbon Bonds in Acetyl-Coenzyme A Synthases/Carbon Monoxide Dehydrogenases" Met. Ions Life Sci. 2009, volume 6, pp. 133–150. 〕 The pathway occurs in bacteria and archaea, e.g. methanogens and in acetate-producing bacteria such as ''Clostridium''. Unlike the Reverse Krebs cycle and the Calvin cycle, this process is not cyclic. ==See also== * Carbon fixation * Carbon monoxide dehydrogenase * Syngas fermentation 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Wood–Ljungdahl pathway」の詳細全文を読む スポンサード リンク
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